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The democratization of higher education means that fewer students are coming to college from socially and economically privileged backgrounds. This is important for diversifying the STEM workforce and improving access to education for all students. Yet, it means that our students vary widely in their levels of preparation for college. Poor preparation leads to failure or withdrawal, especially in introductory level science and math courses, which results in students taking longer to graduate, leaving STEM fields, and leaving college altogether. Excitingly, a growing body of research has revealed strategies for helping students who vary in their preparation to be successful.