Scientists Discover Molecular Culprits Linked to Alcohol Use Disorders
An unanswered question in alcoholism research has been what drives the transition from moderate alcohol consumption to alcohol dependence. Researchers at The University of Texas at Austin set out to discover if a molecule that regulates gene expression in the brain called Lim-only 4 (Lmo4) could facilitate this transition. In doing so, they discovered a molecular mechanism in the brain that is critical to the development of alcoholism, providing potential new targets for treatment.