Updated on August 31, 2018: This release was updated to correct mistakes in descriptions of the way cancer cells develop drug resistance and the way that anti-cancer drug DCA affects the metabolism of cancer cells.
The chemical structure of C1, a drug combining two active elements: Doxorubicin (Dox), a powerful cancer chemotherapy agent that's been used for decades; and a dichloroacetic acid (DCA) subunit, which reverses a cell's metabolism to aerobic. Credit: University of Texas at Austin
A new drug lead shows promise that it could reduce the size of cancerous tumors much more effectively than current treatments.
For years, scientists have looked at human chromosomes, and the DNA they carried, poring over the genetic code that makes up every cell for clues about everything from our eye color to congenital diseases. In a new study, however, scientists have demonstrated the movement of chromosomes within cells also may play a role in human traits and health.
Joanne Ravel (PhD '54), Ashbel Smith Professor Emeritus at the University of Texas at Austin, passed away on June 28, 2018 just shy of her 94th birthday. She was a lifelong resident of Austin, Texas.
Researchers at The University of Texas at Austin have designed a way to sense dangerous chemicals using, in part, a simple rig consisting of a smartphone and a box made from Lego bricks, which could help first responders and scientists in the field identify deadly and difficult-to-detect nerve agents such as VX and sarin. The new methodology described in a paper published Wednesday in the open-access journal ACS Central Science combines a chemical sensor with photography to detect and identify different nerve agents — odorless, tasteless chemical weapons that can cause severe illness and death, sometimes within minutes.
Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink. Photo credit: Shutterstock.
Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink. If eventually brought to market, it could help the more than 15 million Americans, and many more around the world who suffer from alcoholism stay sober.
Using a computer simulation that models the physical and chemical interactions of cancerous cells (colored dots), researchers discovered that over time, tumors develop a distinctive two-part structure: slow moving cells moving randomly in a dense core (blue and purple), surrounded by a band of cells moving faster and more directly outward (green, yellow, red). Arrows indicate direction of motion. The image at right is the same tumor cut in half to reveal the inner structure. Image credit: Anne Bowen, Texas Advanced Computing Center at the University of Texas at Austin.
Scientists have recently discovered a method in cancer's madness. Before now, they've been perplexed by how cancer cells, growing alongside healthy cells, often spread much faster into surrounding tissue than randomness would dictate. It's as if cancerous cells are intentionally moving directly outward, invading healthy tissue.
A University of Texas at Austin professor and her team were honored with a prestigious SXSW Interactive Innovation Award for the MasSpec Pen, a device that will allow surgeons to identify cancerous tissue in seconds.
Jonathan Sessler was a college student when he was first diagnosed with Hodgkin's lymphoma. Fortunately, he was also a chemistry major. After surviving radiation therapy, relapsing and then surviving extremely high doses of what he calls "rat poison" (a.k.a. chemotherapy), his oncologist challenged him: "You're a chemist. Find new cancer drugs."
Three awards totaling $3.19 million from the Cancer Prevention and Research Institute of Texas (CPRIT) will support cancer research in The University of Texas at Austin's Departments of Molecular Biosciences and Chemistry.
Chip McElroy came to the University of Texas at Austin in 1975 and left in 1988 with a PhD in biochemistry. After a career in biotech and drug design, he left behind molecular biology and co-founded Live Oak Brewing Company 22 years ago. That was back before anyone knew what craft brewing was in Austin. McElroy is putting that chemistry knowledge to good use now at Austin's oldest brewery.
With the prick of a finger, the new sensor could indicate whether a person has elevated levels of a biomarker associated with heart failure. Credit: iStock.
The National Institutes of Health (NIH) has awarded a team led by Richard M. Crooks, a chemistry professor at The University of Texas at Austin, a $2 million grant to develop an inexpensive, at-home test for people diagnosed with heart failure.
A team of scientists and engineers at The University of Texas at Austin has invented a powerful tool that rapidly and accurately identifies cancerous tissue during surgery, delivering results in about 10 seconds—more than 150 times as fast as existing technology. The MasSpec Pen is an innovative handheld instrument that gives surgeons precise diagnostic information about what tissue to cut or preserve, helping improve treatment and reduce the chances of cancer recurrence.
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