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How do brain cells (neurons) and their connections (synapses) mediate learning and memory?

Synapses form neural circuits in the brain. Nanoscale imaging in the electron microscope is needed to determine where synapses are located and whether changes in synapse structure and composition are associated with learning and memory. Students engaged in this stream learn to identify, reconstruct in 3D, measure and analyze neuronal structures including: dendrites, axons, synapses, and subcellular components involved in synapse function. Opportunities exist to engineer improved computer imaging tools. Projects provide a strong foundation for understanding fundamental brain mechanisms.

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